Additional Info
Properties
- MOTS-C Chemical Formula: C101H152N28O22S2
- MOTS-C Molecular Weight: 2174.64 g/mol
- MOTS-C Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
- Total Amount of the Active Ingredient: 10 mg (1 vial)
- Shelf Life: 36 months
Shipping
- USA, Canada
- If your shipment is seized (International Orders), we will provide a 50% discount applicable on your next purchase. Please contact us for more information.
Disclaimer
The information provided above does not substitute medical advice, diagnosis, or treatment. For any concerns regarding a medical condition, consult your physician or a qualified healthcare provider promptly. Never disregard professional medical advice or delay seeking it based on information you have read or seen. We do not assume any responsibility or liability for the use of our research compounds and products. These products are exclusively intended for research purposes and are not suitable for human consumption.
Additional Label & Product Information
Essential Warning:
These chemicals are for research or laboratory use only and are not approved by the FDA for human consumption.
Usage Instructions:
Avoid contact with skin and eyes. In case of contact, rinse thoroughly with water. Seek medical assistance if you experience discomfort or accidental ingestion.
Store the lyophilized (freeze-dried) peptide at room temperature upon receipt. Avoid frequent freeze-thaw cycles to maintain peptide stability.
Product Disclaimer:
This product is not intended to diagnose, treat, cure, or prevent any disease. Use strictly according to specific research or laboratory protocols.
Resources
- Lu H, Wei M, Zhai Y, Li Q, Ye Z, Wang L, Luo W, Chen J, Lu Z. MOTS-c peptide regulates adipose homeostasis to prevent ovariectomy-induced metabolic dysfunction. J Mol Med (Berl). 2019 Apr;97(4):473-485. doi: 10.1007/s00109-018-01738-w. Epub 2019 Feb 6. PMID: 30725119.
- Kim KH, Son JM, Benayoun BA, Lee C. The Mitochondrial-Encoded Peptide MOTS-c Translocates to the Nucleus to Regulate Nuclear Gene Expression in Response to Metabolic Stress. Cell Metab. 2018 Sep 4;28(3):516-524.e7. doi: 10.1016/j.cmet.2018.06.008. Epub 2018 Jul 5. PMID: 29983246; PMCID: PMC6185997.
- Cataldo LR, Fernández-Verdejo R, Santos JL, Galgani JE. Plasma MOTS-c levels are associated with insulin sensitivity in lean but not in obese individuals. J Investig Med. 2018 Aug;66(6):1019-1022. doi: 10.1136/jim-2017-000681. Epub 2018 Mar 27. PMID: 29593067.
- Lee C, Kim KH, Cohen P. MOTS-c: A novel mitochondrial-derived peptide regulating muscle and fat metabolism. Free Radic Biol Med. 2016 Nov;100:182-187. doi: 10.1016/j.freeradbiomed.2016.05.015. Epub 2016 May 20. PMID: 27216708; PMCID: PMC5116416.
- Che N, Qiu W, Wang JK, Sun XX, Xu LX, Liu R, Gu L. MOTS-c improves osteoporosis by promoting the synthesis of type I collagen in osteoblasts via TGF-β/SMAD signaling pathway. Eur Rev Med Pharmacol Sci. 2019 Apr;23(8):3183-3189. doi: 10.26355/eurrev_201904_17676. PMID: 31081069.
- Hu BT, Chen WZ. MOTS-c improves osteoporosis by promoting osteogenic differentiation of bone marrow mesenchymal stem cells via TGF-β/Smad pathway. Eur Rev Med Pharmacol Sci. 2018 Nov;22(21):7156-7163. doi: 10.26355/eurrev_201811_16247. PMID: 30468456.
- Qin Q, Delrio S, Wan J, Jay Widmer R, Cohen P, Lerman LO, Lerman A. Downregulation of circulating MOTS-c levels in patients with coronary endothelial dysfunction. Int J Cardiol. 2018 Mar 1;254:23-27. doi: 10.1016/j.ijcard.2017.12.001. Epub 2017 Dec 6. PMID: 29242099.
- Fuku N, Pareja-Galeano H, Zempo H, Alis R, Arai Y, Lucia A, Hirose N. The mitochondrial-derived peptide MOTS-c: a player in exceptional longevity? Aging Cell. 2015 Dec;14(6):921-3. doi: 10.1111/acel.12389. Epub 2015 Aug 20. PMID: 26289118; PMCID: PMC4693465.
Reviews
There are no reviews yet.